Phosphorylation of the androgen receptor is associated with reduced survival in hormone-refractory prostate cancer patients

Cell line studies demonstrate that the PI3K/Akt pathway is upregulated in hormone-refractory prostate cancer (HRPC) and can result in phosphorylation of the androgen receptor (AR). The current study therefore aims to establish if this has relevance to the development of clinical HRPC. Immunohistoche...

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Autori principali: McCall, P, Gemmell, L K, Mukherjee, R, Bartlett, J M S, Edwards, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275485/
https://ncbi.nlm.nih.gov/pubmed/18349820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604152
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