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The androgen receptor in hormone-refractory prostate cancer

Advanced prostate cancer is responsive to hormone therapy that interferes with androgen receptor (AR) signalling. However, the effect is short-lived, as nearly all tumours progress to a hormone-refractory (HR) state, a lethal stage of the disease. Intuitively, the AR should not be involved because h...

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Detalhes bibliográficos
Main Authors: Mao, Hai-Lei, Zhu, Zhi-Qi, Chen, Charlie Degui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735219/
https://ncbi.nlm.nih.gov/pubmed/19050686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2008.14
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