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NleB, a bacterial effector with glycosyltransferase activity targets GADPH function to inhibit NF-κB activation

Modulation of NF-κB-dependent responses is critical to the success of attaching/effacing (A/E) human pathogenic E. coli (EPEC and EHEC) and the natural mouse pathogen Citrobacter rodentium. NleB, a highly conserved type III secretion system effector of A/E pathogens, suppresses NF-κB activation, but...

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Bibliografske podrobnosti
Main Authors:	Gao, Xiaofei, Wang, Xiaogang, Pham, Thanh H., Feuerbacher, Leigh Ann, Lubos, Marie-Luise, Huang, Minzhao, Olsen, Rachel, Mushegian, Arcady, Slawson, Chad, Hardwidge, Philip R.
Format:	Artigo
Jezik:	Inglês
Izdano:	2013
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3553500/ https://ncbi.nlm.nih.gov/pubmed/23332158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.11.010
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NleB, a bacterial effector with glycosyltransferase activity targets GADPH function to inhibit NF-κB activation

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