Citrobacter rodentium NleB Protein Inhibits Tumor Necrosis Factor (TNF) Receptor-associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production

Interferon signaling plays important roles in both intestinal homeostasis and in the host response to pathogen infection. The extent to which bacterial pathogens inhibit this host pathway is an understudied area of investigation. We characterized Citrobacter rodentium strains bearing deletions in in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Gao, Xiaofei, Pham, Thanh H., Feuerbacher, Leigh Ann, Chen, Kangming, Hays, Michael P., Singh, Gyanendra, Rueter, Christian, Hurtado-Guerrero, Ramon, Hardwidge, Philip R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Microbiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000071/
https://ncbi.nlm.nih.gov/pubmed/27387501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738278
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