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Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes

Nuclear pore complexes (NPCs) control the traffic between cell nucleus and cytoplasm. While facilitating translocation of nuclear transport receptors (NTRs) and NTR·cargo complexes, they suppress passive passage of macromolecules ⩾30 kDa. Previously, we reconstituted the NPC barrier as hydrogels com...

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Main Authors: Labokha, Aksana A, Gradmann, Sabine, Frey, Steffen, Hülsmann, Bastian B, Urlaub, Henning, Baldus, Marc, Görlich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553378/
https://ncbi.nlm.nih.gov/pubmed/23202855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.302
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