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Alternative lengthening of telomeres in normal mammalian somatic cells
Some cancers use alternative lengthening of telomeres (ALT), a mechanism whereby new telomeric DNA is synthesized from a DNA template. To determine whether normal mammalian tissues have ALT activity, we generated a mouse strain containing a DNA tag in a single telomere. We found that the tagged telo...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553280/ https://ncbi.nlm.nih.gov/pubmed/23307865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.205062.112 |
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