Coexistence of Alternative Lengthening of Telomeres and Telomerase in hTERT-Transfected GM847 Cells

It has been shown previously that some immortalized human cells maintain their telomeres in the absence of significant levels of telomerase activity by a mechanism referred to as alternative lengthening of telomeres (ALT). Cells utilizing ALT have telomeres of very heterogeneous length, ranging from...

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Autors principals: Perrem, Kilian, Colgin, Lorel M., Neumann, Axel A., Yeager, Thomas R., Reddel, Roger R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87050/
https://ncbi.nlm.nih.gov/pubmed/11359895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.12.3862-3875.2001
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