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Correct Timing of Proliferation and Differentiation is Necessary for Normal Inner Ear Development and Auditory Hair Cell Viability

BACKGROUND: Hearing restoration through hair cell regeneration will require revealing the dynamic interactions between proliferation and differentiation during development to avoid the limited viability of regenerated hair cells. Pax2-Cre N-Myc conditional knockout (CKO) mice highlighted the need of...

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Detalhes bibliográficos
Main Authors: Kopecky, Benjamin J., Jahan, Israt, Fritzsch, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553268/
https://ncbi.nlm.nih.gov/pubmed/23193000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23910
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