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Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation

The innervation of the inner ear critically depends on the two neurotrophins Ntf3 and Bdnf. In contrast to this molecularly well-established dependency, evidence regarding the need of innervation for long-term maintenance of inner ear hair cells is inconclusive, due to experimental variability. Muta...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Kersigo, Jennifer, Fritzsch, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364252/
https://ncbi.nlm.nih.gov/pubmed/25852547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00033
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