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ATM impacts IGF-1 signaling in skeletal muscle
Reports that ataxia telangiectasia mutated (ATM) is required for full activation of Akt raise the hypothesis that ATM plays a role in IGF-1 signaling through the Akt/mTOR pathway. Differentiated C2C12 cells harboring either ATM-targeting shRNA or non-targeting shRNA and myotubes from a C2C12 lineage...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553258/ https://ncbi.nlm.nih.gov/pubmed/22941977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2012.066357 |
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