Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages

BACKGROUND: HIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases. We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammatory response through inhibiting endoplasmic retic...

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Detalhes bibliográficos
Main Authors: Zha, Weibin, Wang, Guangji, Xu, Weiren, Liu, Xuyuan, Wang, Yun, Zha, Beth S., Shi, Jian, Zhao, Qijin, Gerk, Phillip M., Studer, Elaine, Hylemon, Phillip B., Pandak, William M., Zhou, Huiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553168/
https://ncbi.nlm.nih.gov/pubmed/23372711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054349
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