Cysteine Depletion Causes Oxidative Stress and Triggers Outer Membrane Vesicle Release by Neisseria meningitidis; Implications for Vaccine Development

Outer membrane vesicles (OMV) contain immunogenic proteins and contribute to in vivo survival and virulence of bacterial pathogens. The first OMV vaccines successfully stopped Neisseria meningitidis serogroup B outbreaks but required detergent-extraction for endotoxin removal. Current vaccines use a...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: van de Waterbeemd, Bas, Zomer, Gijsbert, van den IJssel, Jan, van Keulen, Lonneke, Eppink, Michel H., van der Ley, Peter, van der Pol, Leo A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553081/
https://ncbi.nlm.nih.gov/pubmed/23372704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054314
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires