Tissue-specific expression of p73 C-terminal isoforms in mice

p73 is a p53 family transcription factor. Due to the presence in the 5′ flanking region of two promoters, there are two N-terminal variants, TAp73, which retains a fully active transactivation domain (TA), and ΔNp73, in which the N terminus is truncated. In addition, extensive 3′ splicing gives rise...

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Main Authors: Grespi, Francesca, Amelio, Ivano, Tucci, Paola, Annicchiarico-Petruzzelli, Margherita, Melino, Gerry
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552929/
https://ncbi.nlm.nih.gov/pubmed/23159862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22787
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