BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: Implications for breast cancer prevention with antioxidant therapies

Mutations in the BRCA1 tumor suppressor gene are commonly found in hereditary breast cancer. Similarly, downregulation of BRCA1 protein expression is observed in the majority of basal-like breast cancers. Here, we set out to study the effects of BRCA1 mutations on oxidative stress in the tumor micro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Martinez-Outschoorn, Ubaldo E., Balliet, Renee, Lin, Zhao, Whitaker-Menezes, Diana, Birbe, Ruth C., Bombonati, Alessandro, Pavlides, Stephanos, Lamb, Rebecca, Sneddon, Sharon, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552923/
https://ncbi.nlm.nih.gov/pubmed/23172369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22776
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak