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Epigenetic silencing of Notch signaling in gastrointestinal cancers

The Notch signaling pathway drives proliferation, differentiation, apoptosis, cell fate choices and maintenance of stem cells during embryogenesis and in self-renewing tissues of the adult. In addition, aberrant Notch signaling has been implicated in several tumors, where Notch can function both as...

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Bibliografiske detaljer
Main Authors: Piazzi, Giulia, Bazzoli, Franco, Ricciardiello, Luigi
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552914/
https://ncbi.nlm.nih.gov/pubmed/23085543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22388
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