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Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesis

The Notch cascade is a fundamental and highly conserved pathway able to control cell-fate. The Notch pathway arises from the interaction of one of the Notch receptors (Notch1–4) with different types of ligands; in particular, the Notch pathway can be activated canonically (through the ligands Jagged...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fazio, Chiara, Ricciardiello, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260996/
https://ncbi.nlm.nih.gov/pubmed/27929540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.408
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