Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells

Aberrant NOTCH1 signalling is critically involved in multiple models of colorectal cancer (CRC) and a prominent role of NOTCH1 activity during inflammation has emerged. Epithelial to Mesenchymal Transition (EMT), a crucial event promoting malignant transformation, is regulated by inflammation and Me...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Fazio, Chiara, Piazzi, Giulia, Vitaglione, Paola, Fogliano, Vincenzo, Munarini, Alessandra, Prossomariti, Anna, Milazzo, Maddalena, D’Angelo, Leonarda, Napolitano, Manuela, Chieco, Pasquale, Belluzzi, Andrea, Bazzoli, Franco, Ricciardiello, Luigi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749954/
https://ncbi.nlm.nih.gov/pubmed/26864323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20670
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars