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Activation of autophagy in cells with abnormal karyotype

The presence of even one extra chromosome severely impairs cellular growth. This effect of aneuploidy (a term describing chromosome numbers deviating from multiples of haploid chromosome content) has been observed in many different organisms, from yeast to humans. Accordingly, abnormal karyotypes ar...

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Detalhes bibliográficos
Main Authors: Stingele, Silvia, Stoehr, Gabriele, Storchova, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552891/
https://ncbi.nlm.nih.gov/pubmed/23108329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22558
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