Doxorubicin-loaded cholic acid-polyethyleneimine micelles for targeted delivery of antitumor drugs: synthesis, characterization, and evaluation of their in vitro cytotoxicity

Doxorubicin-loaded micelles were prepared from a copolymer comprising cholic acid (CA) and polyethyleneimine (PEI) for the delivery of antitumor drugs. The CA-PEI copolymer was synthesized via pairing mediated by N,N’-dicyclohexylcarbodiimide and N-hydroxysuccinimide using dichloromethane as a solve...

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Hauptverfasser: Amjad, Muhammad Wahab, Amin, Mohd Cairul Iqbal Mohd, Katas, Haliza, Butt, Adeel Masood
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2012
Schlagworte:
Nano Express
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552841/
https://ncbi.nlm.nih.gov/pubmed/23270381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-7-687
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