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Synergistic effect of pH-responsive folate-functionalized poloxamer 407-TPGS-mixed micelles on targeted delivery of anticancer drugs

BACKGROUND: Doxorubicin (DOX), an anthracycline anticancer antibiotic, is used for treating various types of cancers. However, its use is associated with toxicity to normal cells and development of resistance due to overexpression of drug efflux pumps. Poloxamer 407 (P407) and vitamin E TPGS (D-α-to...

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Foilsithe in:Int J Nanomedicine
Main Authors: Butt, Adeel Masood, Mohd Amin, Mohd Cairul Iqbal, Katas, Haliza
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335624/
https://ncbi.nlm.nih.gov/pubmed/25709451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78438
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