Persistent effects of chronic clozapine on the cellular and behavioral responses to LSD in mice

RATIONALE: In schizophrenia patients, optimal treatment with antipsychotics requires weeks to months of sustained drug therapy. However, single administration of antipsychotic drugs can reverse schizophrenia-like behavioral alterations in rodent models of psychosis. This raises questions about the p...

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Main Authors: Moreno, José L., Holloway, Terrell, Umali, Adrienne, Rayannavar, Vinayak, Sealfon, Stuart C., González-Maeso, Javier
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552490/
https://ncbi.nlm.nih.gov/pubmed/22842765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2809-7
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