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Free Energy Cost of Stretching mRNA Hairpin Loops Inhibits Small RNA Binding
Small RNA-mRNA binding is an essential step in RNA interference, an important cellular regulatory process. Calculations of binding free energy have been used in binding site prediction, but the cost of stretching the mRNA loop when the small RNA-mRNA duplex forms requires further exploration. Here,...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552280/ https://ncbi.nlm.nih.gov/pubmed/23442870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.017 |
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