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A two-length-scale polymer theory for RNA loop free energies and helix stacking

The reliability of RNA secondary structure predictions is subject to the accuracy of the underlying free energy model. Mfold and other RNA folding algorithms are based on the Turner model, whose weakest part is its formulation of loop free energies, particularly for multibranch loops. RNA loops cont...

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Библиографические подробности
Главные авторы: Aalberts, Daniel P., Nandagopal, Nagarajan
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885684/
https://ncbi.nlm.nih.gov/pubmed/20504955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1831710
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