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Nicotinic Receptor Transduction Zone: Invariant Arginine Couples to Multiple Electron-Rich Residues

Gating of the muscle-type acetylcholine receptor (AChR) channel depends on communication between the ACh-binding site and the remote ion channel. A key region for this communication is located within the structural transition zone between the ligand-binding and pore domains. Here, stemming from β-st...

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Autores principales: Mukhtasimova, Nuriya, Sine, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552258/
https://ncbi.nlm.nih.gov/pubmed/23442857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.013
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