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Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

Neutrophil extracellular traps (NETs) represent an important defense mechanism against microorganisms. Clearance of NETs is impaired in a subset of patients with systemic lupus erythematosus (SLE), while NETosis is increased in neutrophils and, particularly, in low-density granulocytes derived from...

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Detalhes bibliográficos
Main Authors: Kahlenberg, J. Michelle, Carmona-Rivera, Carmelo, Smith, Carolyne K., Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552129/
https://ncbi.nlm.nih.gov/pubmed/23267025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202388
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