Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

Neutrophil extracellular traps (NETs) are implicated in autoimmunity but how they are generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune complexes, inducers of NETosis, require mitochondrial ROS for maximal NET stimulation. During this process, mitochondria be...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nat Med
Glavni autori: Lood, Christian, Blanco, Luz P., Purmalek, Monica M., Carmona-Rivera, Carmelo, De Ravin, Suk S., Smith, Carolyne K., Malech, Harry L., Ledbetter, Jeffrey A., Elkon, Keith B., Kaplan, Mariana J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742415/
https://ncbi.nlm.nih.gov/pubmed/26779811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4027
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items