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PERSPECTIVES ON CANCER STEM CELLS IN OSTEOSARCOMA

Osteosarcoma is an aggressive pediatric tumor of growing bones that, despite surgery and chemotherapy, is prone to relapse. These mesenchymal tumors are derived from progenitor cells in the osteoblast lineage that have accumulated mutations to escape cell cycle checkpoints leading to excessive proli...

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Bibliographic Details
Main Authors: Basu-Roy, Upal, Basilico, Claudio, Mansukhani, Alka
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552024/
https://ncbi.nlm.nih.gov/pubmed/22659734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.05.028
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