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PERSPECTIVES ON CANCER STEM CELLS IN OSTEOSARCOMA
Osteosarcoma is an aggressive pediatric tumor of growing bones that, despite surgery and chemotherapy, is prone to relapse. These mesenchymal tumors are derived from progenitor cells in the osteoblast lineage that have accumulated mutations to escape cell cycle checkpoints leading to excessive proli...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552024/ https://ncbi.nlm.nih.gov/pubmed/22659734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.05.028 |
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