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PERSPECTIVES ON CANCER STEM CELLS IN OSTEOSARCOMA

Osteosarcoma is an aggressive pediatric tumor of growing bones that, despite surgery and chemotherapy, is prone to relapse. These mesenchymal tumors are derived from progenitor cells in the osteoblast lineage that have accumulated mutations to escape cell cycle checkpoints leading to excessive proli...

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Detalhes bibliográficos
Main Authors: Basu-Roy, Upal, Basilico, Claudio, Mansukhani, Alka
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552024/
https://ncbi.nlm.nih.gov/pubmed/22659734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.05.028
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