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Targeting Ribosome assembly on the HCV RNA using a small RNA molecule

Translation initiation of hepatitis C Virus (HCV) RNA is the initial obligatory step of the viral life cycle, mediated through the Internal Ribosome Entry Site (IRES) present in the 5′-untranslated region (UTR). Initiation on the HCV IRES is mediated by multiple structure-specific interactions betwe...

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Détails bibliographiques
Auteurs principaux: Bhat, Prasanna, Gnanasundram, Sivakumar Vadivel, Mani, Prashant, Ray, Partho Sarothi, Sarkar, Debi P, Das, Saumitra
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551865/
https://ncbi.nlm.nih.gov/pubmed/22858675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21208
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