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At least two molecules of the RNA helicase Has1 are simultaneously present in pre-ribosomes during ribosome biogenesis

The RNA helicase Has1 is involved in the biogenesis of both small and large ribosomal subunits. How it performs these separate roles is not fully understood. Here we provide evidence that at least two molecules of Has1 are temporarily present at the same time in 90S pre-ribosomes. We identified mult...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gnanasundram, Sivakumar Vadivel, Kos-Braun, Isabelle C, Koš, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846684/
https://ncbi.nlm.nih.gov/pubmed/31511893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz767
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