DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA

Among the proteins predicted to be a part of the DExD box RNA helicase family, the functions of DDX49 are unknown. Here, we characterize the enzymatic activities and functions of DDX49 by comparing its properties with the well-studied RNA helicase, DDX39B. We find that DDX49 exhibits a robust ATPase...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Awasthi, Sharad, Verma, Mamta, Mahesh, Arun, K. Khan, Mohd Imran, Govindaraju, Gayathri, Rajavelu, Arumugam, Chavali, Pavithra L, Chavali, Sreenivas, Dhayalan, Arunkumar
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
RNA and RNA-protein complexes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158705/
https://ncbi.nlm.nih.gov/pubmed/29618122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky231
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