DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA

Among the proteins predicted to be a part of the DExD box RNA helicase family, the functions of DDX49 are unknown. Here, we characterize the enzymatic activities and functions of DDX49 by comparing its properties with the well-studied RNA helicase, DDX39B. We find that DDX49 exhibits a robust ATPase...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Awasthi, Sharad, Verma, Mamta, Mahesh, Arun, K. Khan, Mohd Imran, Govindaraju, Gayathri, Rajavelu, Arumugam, Chavali, Pavithra L, Chavali, Sreenivas, Dhayalan, Arunkumar
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
RNA and RNA-protein complexes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158705/
https://ncbi.nlm.nih.gov/pubmed/29618122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky231
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