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Sulodexide Decreases Albuminuria and Regulates Matrix Protein Accumulation in C57BL/6 Mice with Streptozotocin-Induced Type I Diabetic Nephropathy

OBJECTIVE: Sulodexide is a mixture of glycosaminoglycans that may reduce proteinuria in diabetic nephropathy (DN), but its mechanism of action and effect on renal histology is not known. We investigated the effect of sulodexide on disease manifestations in a murine model of type I DN. METHODS: Male...

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Detalles Bibliográficos
Main Authors: Yung, Susan, Chau, Mel K. M., Zhang, Qing, Zhang, Chen Zhu, Chan, Tak Mao
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551764/
https://ncbi.nlm.nih.gov/pubmed/23349910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054501
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