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Sulodexide Decreases Albuminuria and Regulates Matrix Protein Accumulation in C57BL/6 Mice with Streptozotocin-Induced Type I Diabetic Nephropathy

OBJECTIVE: Sulodexide is a mixture of glycosaminoglycans that may reduce proteinuria in diabetic nephropathy (DN), but its mechanism of action and effect on renal histology is not known. We investigated the effect of sulodexide on disease manifestations in a murine model of type I DN. METHODS: Male...

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Bibliografiske detaljer
Main Authors: Yung, Susan, Chau, Mel K. M., Zhang, Qing, Zhang, Chen Zhu, Chan, Tak Mao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551764/
https://ncbi.nlm.nih.gov/pubmed/23349910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054501
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