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Sulodexide Decreases Albuminuria and Regulates Matrix Protein Accumulation in C57BL/6 Mice with Streptozotocin-Induced Type I Diabetic Nephropathy

OBJECTIVE: Sulodexide is a mixture of glycosaminoglycans that may reduce proteinuria in diabetic nephropathy (DN), but its mechanism of action and effect on renal histology is not known. We investigated the effect of sulodexide on disease manifestations in a murine model of type I DN. METHODS: Male...

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Autors principals: Yung, Susan, Chau, Mel K. M., Zhang, Qing, Zhang, Chen Zhu, Chan, Tak Mao
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551764/
https://ncbi.nlm.nih.gov/pubmed/23349910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054501
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