A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan

BACKGROUND: Pregnancy is associated with an increased risk of developing a malaria infection and a higher risk of developing severe malaria. The pharmacokinetic properties of many anti-malarials are also altered during pregnancy, often resulting in a decreased drug exposure. Piperaquine is a promisi...

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Hlavní autoři: Hoglund, Richard M, Adam, Ishag, Hanpithakpong, Warunee, Ashton, Michael, Lindegardh, Niklas, Day, Nicholas PJ, White, Nicholas J, Nosten, Francois, Tarning, Joel
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551687/
https://ncbi.nlm.nih.gov/pubmed/23190801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-398
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