Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria

Pregnant women are particularly vulnerable to malaria. The pharmacokinetic properties of antimalarial drugs are often affected by pregnancy, resulting in lower drug concentrations and a consequently higher risk of treatment failure. The objective of this study was to evaluate the population pharmaco...

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Detalhes bibliográficos
Main Authors: Tarning, Joel, Rijken, Marcus J., McGready, Rose, Phyo, Aung Pyae, Hanpithakpong, Warunee, Day, Nicholas P. J., White, Nicholas J., Nosten, François, Lindegardh, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318332/
https://ncbi.nlm.nih.gov/pubmed/22252822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05756-11
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