Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria

Pregnant women are particularly vulnerable to malaria. The pharmacokinetic properties of antimalarial drugs are often affected by pregnancy, resulting in lower drug concentrations and a consequently higher risk of treatment failure. The objective of this study was to evaluate the population pharmaco...

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Bibliografiska uppgifter
Huvudupphovsmän: Tarning, Joel, Rijken, Marcus J., McGready, Rose, Phyo, Aung Pyae, Hanpithakpong, Warunee, Day, Nicholas P. J., White, Nicholas J., Nosten, François, Lindegardh, Niklas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318332/
https://ncbi.nlm.nih.gov/pubmed/22252822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05756-11
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