Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Falciparum Malaria

Dihydroartemisinin-piperaquine is a fixed-dose artemisinin-based combination treatment. Some antimalarials have altered pharmacokinetics in pregnancy. Pregnant women in the 2nd or 3rd trimester and matched nonpregnant women with uncomplicated falciparum malaria were treated with a total of 6.4 mg/kg...

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Main Authors: Rijken, Marcus J., McGready, Rose, Phyo, Aung Phae, Lindegardh, Niklas, Tarning, Joel, Laochan, Natthapon, Than, Hla Hla, Mu, Oh, Win, Aye Kyi, Singhasivanon, Pratap, White, Nicholas, Nosten, François
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232755/
https://ncbi.nlm.nih.gov/pubmed/21947392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05067-11
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