Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria

PURPOSE: Dihydroartemisinin-piperaquine (DP) is a fixed-dose artemisinin-based combination treatment. Field pharmacokinetic studies would be simplified and facilitated by being able to use small volume capillary assays rather than venous blood. The aim of this study was to describe the relationship...

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Main Authors: Ashley, Elizabeth A., Stepniewska, Kasia, Lindegardh, Niklas, Annerberg, Anna, Tarning, Joel, McGready, Rose, Phaiphun, Lucy, Singhasivanon, Pratap, White, Nicholas J., Nosten, François
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Pharmacokinetics and Disposition
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883082/
https://ncbi.nlm.nih.gov/pubmed/20300743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-010-0804-7
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