Population Pharmacokinetic Assessment of a New Regimen of Mefloquine Used in Combination Treatment of Uncomplicated Falciparum Malaria

A fixed artesunate-mefloquine combination, comprising three daily doses of 8 mg of mefloquine/kg of body weight and 4 mg of artesunate/kg, has been developed recently. This study was designed to construct a population pharmacokinetic model describing this new dosage regimen of mefloquine given as lo...

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Autors principals: Ashley, Elizabeth A., Stepniewska, Kasia, Lindegårdh, Niklas, McGready, Rose, Hutagalung, Robert, Hae, Rae, Singhasivanon, Pratap, White, Nicholas J., Nosten, François
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Clinical Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489761/
https://ncbi.nlm.nih.gov/pubmed/16801402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00040-06
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