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NK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation

2B4 (CD244) and NK-T-B-antigen (NTB-A, CD352) are activating receptors on human natural killer (NK) cells and belong to the family of signaling lymphocyte activation molecule (SLAM)-related receptors (SRR). Engagement of these receptors leads to phosphorylation of their cytoplasmic tails and recruit...

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Detalhes bibliográficos
Main Authors: Meinke, Stephan, Watzl, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551190/
https://ncbi.nlm.nih.gov/pubmed/23346089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00003
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