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NK cells switch from granzyme B to death receptor–mediated cytotoxicity during serial killing
NK cells eliminate virus-infected and tumor cells by releasing cytotoxic granules containing granzyme B (GrzB) or by engaging death receptors that initiate caspase cascades. The orchestrated interplay between both cell death pathways remains poorly defined. Here we simultaneously measure the activit...
Gardado en:
| Publicado en: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719417/ https://ncbi.nlm.nih.gov/pubmed/31270246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181454 |
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