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Global analysis of B cell selection using an immunoglobulin light chain–mediated model of autoreactivity
The important subtleties of B cell tolerance are best understood in a diverse immunoglobulin (Ig) repertoire context encoding a full spectrum of autoreactivity. To achieve this, we used mice expressing Igκ transgenes that confer varying degrees of autoreactivity within a diverse heavy chain (HC) rep...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549719/ https://ncbi.nlm.nih.gov/pubmed/23267014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120525 |
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