Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are profoundly diminished and prone to apoptotic deletion. In this study, we investigate whether the large population of activated NK cells in the human liver contributes to this process. We show that in vitr...

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Autors principals: Peppa, Dimitra, Gill, Upkar S., Reynolds, Gary, Easom, Nicholas J.W., Pallett, Laura J., Schurich, Anna, Micco, Lorenzo, Nebbia, Gaia, Singh, Harsimran D., Adams, David H., Kennedy, Patrick T.F., Maini, Mala K.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549717/
https://ncbi.nlm.nih.gov/pubmed/23254287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121172
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