Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection

NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill hepatocytes bearing TRAIL receptors. In this stud...

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Detalhes bibliográficos
Main Authors: Peppa, Dimitra, Micco, Lorenzo, Javaid, Alia, Kennedy, Patrick T. F., Schurich, Anna, Dunn, Claire, Pallant, Celeste, Ellis, Gidon, Khanna, Pooja, Dusheiko, Geoffrey, Gilson, Richard J., Maini, Mala K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003000/
https://ncbi.nlm.nih.gov/pubmed/21187913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001227
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