Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo

NK cells are important antiviral effectors, highly enriched in the liver, with the potential to regulate immunopathogenesis in persistent viral infections. Here we examined whether changes in the NK pool are induced when patients with eAg-positive CHB are ‘primed’ with PegIFNα and importantly, wheth...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Gill, Upkar S., Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D., Carey, Ivana, Foster, Graham R., Maini, Mala K., Kennedy, Patrick T. F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972354/
https://ncbi.nlm.nih.gov/pubmed/27487232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005788
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