Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo

NK cells are important antiviral effectors, highly enriched in the liver, with the potential to regulate immunopathogenesis in persistent viral infections. Here we examined whether changes in the NK pool are induced when patients with eAg-positive CHB are ‘primed’ with PegIFNα and importantly, wheth...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Gill, Upkar S., Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D., Carey, Ivana, Foster, Graham R., Maini, Mala K., Kennedy, Patrick T. F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972354/
https://ncbi.nlm.nih.gov/pubmed/27487232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005788
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