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The Gate that Governs Sulfotransferase Selectivity

Human cytosolic sulfotransferases (SULTs) transfer the sulfuryl-moiety (-SO(3)) from activated sulfate (3′-phosphoadenosine 5′-phosphosulfate, PAPS) to the hydroxyls and primary amines of numerous metabolites, drugs and xenobiotics. Receipt of the sulfuryl-group often radically alters acceptor-targe...

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Main Authors: Cook, Ian, Wang, Ting, Almo, Steven C., Kim, Jungwook, Falany, Charles N., Leyh, Thomas S.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549632/
https://ncbi.nlm.nih.gov/pubmed/23256751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301492j
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