The Gate that Governs Sulfotransferase Selectivity

Human cytosolic sulfotransferases (SULTs) transfer the sulfuryl-moiety (-SO(3)) from activated sulfate (3′-phosphoadenosine 5′-phosphosulfate, PAPS) to the hydroxyls and primary amines of numerous metabolites, drugs and xenobiotics. Receipt of the sulfuryl-group often radically alters acceptor-targe...

Full description

Saved in:
Bibliographic Details
Main Authors: Cook, Ian, Wang, Ting, Almo, Steven C., Kim, Jungwook, Falany, Charles N., Leyh, Thomas S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549632/
https://ncbi.nlm.nih.gov/pubmed/23256751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301492j
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items