Carbocyclic Analogues of Inosine-5’-Monophosphate: Synthesis and Biological Activity

9-(4’-Phosphonomethoxy-2’-cyclopenten-1’-yl)hypoxanthine and 9-(4’-phosphonomethoxy-2’,3’-dihydroxycyclopenten-1’-yl)hypoxanthine were synthesized as isosteric carbocyclic analogues of inosine-5’-monophosphate. The synthesized compounds were shown to be capable of inhibiting the activity of human ty...

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Autors principals: Matyugina, E.S., Andreevskaya, S.N., Smirnova, T.G., Khandazhinskaya, A.L.
Format: Artigo
Idioma:Inglês
Publicat: A.I. Gordeyev 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549521/
https://ncbi.nlm.nih.gov/pubmed/23346382
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